Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets)

Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets)

Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) contains two active ingredients Lopinavir and Ritonavir.  It is mainly used to treat people with human immunodeficiency virus (HIV) infection. You can buy Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) online also.

This medication is an HIV-1 protease inhibitor which is used in combination with other antiretroviral agents for HIV-1 infection treatment in adults and paediatric patients 14 days and older.

Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) used for?

Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) are a fixed dose combination treatment for Human Immunodeficiency Virus (HIV) infection in adults over and children over 6 months. Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) are used in combination with other medications that have a different mechanism of action to the components in Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets), and are used to treat patients with HIV infection who have either already received treatment with other medications for HIV or as first line therapy for treatment-inexperienced patients. HIV impairs the immune system by attacking specific immune cells called CD4+ cells that are involved in fighting infection and this can lead to opportunistic life-threatening infection (infections that would not normally be harmful); also if too many CD4+ cells are destroyed this can result in acquired immune deficiency syndrome (AIDS). Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) prevent or slow down the ability of HIV to replicate and spread, which keeps the amount virus down to a low level and this results in an increase in CD4+ cell numbers, so that the immune system can recover, reducing the risk of disease progression.

Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) work?

Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) contain lopinavir and ritonavir, which are both inhibitors of HIV protease and are only effective against RNA viruses (retroviruses) like Human Immunodeficiency Virus (HIV). Retroviruses convert RNA to DNA, by the action of the viral-specific enzyme reverse transcriptase (RT). The viral DNA is then integrated into the DNA of infected immune cells so that the virus can replicate. Most of the antiviral activity of Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) is due to lopinavir, which is a potent inhibitor of HIV protease, and prevents cleavage of the Gag-Pol polyprotein, an important protein in the development of active virus. The viral protease enzyme cleaves (breaks down) the Gag-Pol polyprotein during final stages of the replication cycle so that fully active mature virus can be released to infect new cells. Inhibition of protease cleavage by Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) results in the production of immature, non-infectious viral particles. Ritonavir in Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) is included in the combination not as a protease inhibitor but because it inhibits the CYP3A-mediated metabolism (breakdown in the liver) of lopinavir, thereby increasing the plasma levels of lopinavir so that lopinavir can be used at a lower dose. Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) are used in combination with other retrovirals that have a different mechanism of action, like emtricitabine and tenofovir, both nucleoside reverse transcriptase inhibitor (NRTI) that work by blocking the action of RT, inhibiting viral replication. The combined action of lopinavir and ritonavir in Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets), in conjunction with other retroviral drugs, inhibits the production of active HIV so that the viral load (amount of virus) is reduced. Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) slow down the replication of HIV within your body but does not kill the virus already incorporated in the CD4+ cells or prevent the spread of the infection to others.

Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) Side Effects

• The most common Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets) side effects occurring in 5% or more of the patients undergoing treatment with this medication were diarrhea, nausea, abdominal pain, asthenia, vomiting, headache, and dyspepsia.
• The most commonly reported Generic Kaletra side effects of moderate severity that are thought to be drug related are: abdominal pain, abnormal stools (bowel movements), diarrhea, feeling tired, headache, and nausea. Children taking this medicine may sometimes get a skin rash.
• Blood tests in patients taking this medicine may show possible liver problems. People with liver disease such as Hepatitis B and Hepatitis C who take this medicine may have worsening liver disease. Liver problems including death have occurred in patients taking this medicine. In studies, it is unclear if this medicine caused these liver problems because some patients had other illnesses or were taking other medicines.
• Some patients taking this medicine can develop serious problems with their pancreas (pancreatitis), which may cause death. You have a higher chance of having pancreatitis if you have had it before. Tell your doctor if you have nausea, vomiting, or abdominal pain. These may be signs of pancreatitis.
• Some patients have large increases in triglycerides and cholesterol. The long-term chance of getting complications such as heart attacks or stroke due to increases in triglycerides and cholesterol caused by protease inhibitors is not known at this time.
• Diabetes and high blood sugar (hyperglycemia) occur in patients taking protease inhibitors such as this medicine. Some patients had diabetes before starting protease inhibitors, others did not. Some patients need changes in their diabetes medicine. Others needed new diabetes medicine.
• Changes in body fat have been seen in some patients taking antiretroviral therapy. These changes may include increased amount of fat in the upper back and neck ("buffalo hump"), breast, and around the trunk. Loss of fat from the legs, arms and face may also happen. The cause and long term health effects of these conditions are not known at this time.
• Some patients with hemophilia have increased bleeding with protease inhibitors. There have been other side effects in patients taking this medicine. However, these side effects may have been due to other medicines that patients were taking or to the illness itself. Some of these side effects can be serious. If you suspect that you took more than the prescribed dose of this medicine, contact your local poison control center or emergency room immediately. As with all prescription medicines, this medicine should be kept out of the reach of young children.

What medications interact with Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets)?

Always inform your physician about the drugs you are taking till date. Provide complete list of prescription or non prescription drugs and any other disease. This way, your physician will assist you with the list of medicine and other things that may interact with Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets).

Warnings & Precautions When Using Lopimune (Lopinavir 200mg and Ritonavir 50mg Tablets)

• Do not take this medicine if you have had a serious allergic reaction to Lopinavir or Ritonavir (the active ingredients).
• This medicine may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether this medicine passes into breast milk or if it could harm a nursing baby.
• You should tell your doctor if you have liver problems or are infected with Hepatitis B or Hepatitis C.
• Some people taking protease inhibitors develop new or more serious diabetes or high blood sugar. Be sure to tell your doctor if you have diabetes or an increase in thirst and/or frequent urination. Some people with hemophilia have had increased bleeding. It is not known whether the protease inhibitors caused these problems. Be sure to tell your doctor if you have hemophilia types A and B. Together with your doctor, you need to decide whether this medicine is right for you.
• Do not take this medicine if you are taking certain other medicines. These could cause serious side effects that could cause death. Before you take this medicine, you must tell your doctor about all the medicines you are taking or are planning to take.

• Availability: In Stock
• Model: Lopimune
• Brand: Cipla